I have had **** breakout issues since about age 20 and am now in my mid-30s. Recently I started to have systic **** breakouts pretty relentlessly. It did take about three full months of taking the supplements for them to kick in, but they have worked wonders. I have fewer breakouts, they're less bad, and they clear up much more quickly. I would definitely recommend trying the supplements and make sure to give them at least three months.